Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.61 |
| ▸ | SCN1A | P35498 | 3/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.61 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | THPO | P40225 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670218 | 0.95 | SCN1A (0.61) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL4667564 | 0.90 | SCN1A (0.65) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL14380220 | 0.89 | SCN1A (0.52) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL14160114 | 0.88 | SCN1A (0.55) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL14160145 | 0.87 | HTR2A (0.53) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL6976130 | 0.87 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL10356352 | 0.87 | SCN1A (0.53) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL7949004 | 0.87 | SCN1A (0.53) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL4667514 | 0.87 | SCN1A (0.53) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A | |
| SCHEMBL3333232 | 0.87 | SCN1A (0.53) | SLC6A2SLC6A4SLC6A3SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |
| EP-0983222-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052898-A9 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998052898-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 1998-11-26 | — | — | WO | disclosed |