Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.30 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835275 | 0.90 | PPARG (0.31) | PPARGPPARA | |
| SCHEMBL2835279 | 0.86 | — | — | |
| SCHEMBL177246 | 0.84 | — | — | |
| SCHEMBL177247 | 0.80 | — | — | |
| SCHEMBL177244 | 0.78 | ACKR3 (0.44) | ACKR3S1PR1 | |
| SCHEMBL177299 | 0.75 | FFAR1 (0.39) | — | |
| SCHEMBL177580 | 0.68 | S1PR1 (0.42) | ACKR3S1PR1 | |
| SCHEMBL12038120 | 0.67 | MAOA (0.38) | S1PR1PPARG | |
| SCHEMBL177055 | 0.66 | S1PR1 (0.38) | ACKR3S1PR1 | |
| SCHEMBL177102 | 0.65 | CYP26A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | claimed |