Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30021611 | 0.87 | NR1H2 (0.44) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL1442720 | 0.87 | NR1H2 (0.44) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL1439452 | 0.87 | NR1H2 (0.44) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL16772757 | 0.87 | CTSK (0.39) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL30021979 | 0.87 | NR1H2 (0.44) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL1439381 | 0.85 | CTSK (0.38) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL9382870 | 0.85 | CTSK (0.38) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL29279234 | 0.85 | CTSK (0.38) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL1946153 | 0.85 | CTSK (0.38) | CTSKNR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL1439283 | 0.85 | CTSK (0.38) | CTSKNR1H2MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770224-B | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-110770224-A | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2020-02-07 | — | — | CN | disclosed |