Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.52 |
| ▸ | MAOA | P21397 | 11/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358642 | 0.82 | ALDH1A1 (0.41) | MAOBMAOAALDH1A1 | |
| SCHEMBL28355136 | 0.81 | AHR (0.42) | MAOBMAOAALDH1A1MAPT | |
| SCHEMBL28354633 | 0.80 | BRD4 (0.49) | MAOBMAOACREBBPALDH1A1MAPT | |
| SCHEMBL28354632 | 0.80 | SMN1; SMN2 (0.45) | MAOBMAOACREBBPALDH1A1MAPT | |
| SCHEMBL28358735 | 0.73 | CMA1 (0.42) | MAOBMAOAALDH1A1MAPT | |
| SCHEMBL4751126 | 0.70 | MAOB (0.78) | MAOBMAOAPDE3BPDE3ACREBBP | |
| SCHEMBL28354703 | 0.69 | ALDH1A1 (0.41) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL2236580 | 0.69 | MAOB (1.00) | MAOBMAOACREBBP | |
| SCHEMBL689457 | 0.69 | MAOB (0.62) | MAOBMAOAPDE3BPDE3AMAPT | |
| SCHEMBL28882918 | 0.68 | CDK5 (0.45) | CREBBPALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749045-B | D-amino acid oxidase inhibitor and preparation method and application thereof | 上海交通大学 | 2020-02-14 | — | — | CN | disclosed |