Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385006 | 0.96 | MEN1 (0.46) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL29025634 | 0.88 | MEN1 (0.39) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL20120933 | 0.82 | MEN1 (0.34) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL9340198 | 0.77 | POLB (0.40) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27131193 | 0.77 | KDM4E (0.33) | KMT2ARAB9AKDM4EMAPK1ALDH1A1 | |
| SCHEMBL32681962 | 0.77 | MPL (0.36) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2410260 | 0.77 | KDM4E (0.38) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20305757 | 0.76 | MEN1 (0.46) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL30011160 | 0.76 | PDIA6 (0.38) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL11505371 | 0.75 | PDIA6 (0.34) | L3MBTL1ADRB2ADRB1ADRB3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110753693-A | EGFR proteolytic targeting chimeric molecules and related methods of use | 阿尔维纳斯运营股份有限公司 | 2020-02-04 | — | — | CN | disclosed |