Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355010 | 1.00 | SMYD3 (0.46) | SMYD3SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL28354935 | 0.88 | TAS1R3 (0.43) | SMN1; SMN2RAB9AHPGDNPC1ALDH1A1 | |
| SCHEMBL20601249 | 0.88 | TAS1R3 (0.43) | SMN1; SMN2RAB9AHPGDNPC1ALDH1A1 | |
| SCHEMBL20601270 | 0.86 | KDM4E (0.45) | SMYD3SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL20601274 | 0.86 | KDM4E (0.45) | SMYD3SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL20601331 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AHPGDTP53ALDH1A1 | |
| SCHEMBL20601330 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AHPGDTP53ALDH1A1 | |
| SCHEMBL28354846 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AHPGDTP53ALDH1A1 | |
| SCHEMBL20601328 | 0.84 | SMYD3 (0.44) | SMYD3SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL20601215 | 0.84 | SMYD3 (0.44) | SMYD3SMN1; SMN2RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770222-A | Modulators of indoleamine2, 3-dioxygenase | 葛兰素史克知识产权开发有限公司 | 2020-02-07 | — | — | CN | disclosed |