Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111238 | 1.00 | GPR119 (0.48) | GPR119KDM4EPKMMMP13GPR183 | |
| SCHEMBL20618534 | 0.92 | GPR119 (0.48) | GPR119KDM4EPKMMMP13PIK3CD | |
| SCHEMBL20601460 | 0.92 | GPR119 (0.48) | GPR119KDM4EPKMMMP13PIK3CD | |
| SCHEMBL20618547 | 0.92 | GPR119 (0.48) | GPR119KDM4EPKMMMP13KMT2A | |
| SCHEMBL20618538 | 0.92 | GPR119 (0.48) | GPR119KDM4EPKMMMP13PIK3CD | |
| SCHEMBL20601462 | 0.90 | GPR119 (0.47) | GPR119KDM4EPKMMMP13PIK3CD | |
| SCHEMBL20601212 | 0.89 | GPR183 (0.46) | GPR183MAPK1 | |
| SCHEMBL20601216 | 0.89 | GPR183 (0.46) | GPR183MAPK1 | |
| SCHEMBL20601240 | 0.86 | KDM4E (0.50) | GPR119KDM4EPKMMMP13KMT2A | |
| SCHEMBL23088074 | 0.86 | KDM4E (0.50) | GPR119KDM4EPKMMMP13KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770222-A | Modulators of indoleamine2, 3-dioxygenase | 葛兰素史克知识产权开发有限公司 | 2020-02-07 | — | — | CN | disclosed |