Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.40 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20618507 | 1.00 | ITGB1 (0.40) | ITGB1ITGA4GPR119SLC8A1GRIN2B | |
| SCHEMBL20601420 | 0.90 | ITGB1 (0.44) | ITGB1ITGA4SLC8A1MMP13 | |
| SCHEMBL20601416 | 0.90 | ITGB1 (0.44) | ITGB1ITGA4SLC8A1MMP13 | |
| SCHEMBL20601286 | 0.90 | MMP13 (0.45) | ITGB1ITGA4GPR119SLC8A1MMP13 | |
| SCHEMBL20601285 | 0.90 | MMP13 (0.45) | ITGB1ITGA4GPR119SLC8A1MMP13 | |
| SCHEMBL20618714 | 0.90 | MMP13 (0.45) | ITGB1ITGA4GPR119SLC8A1MMP13 | |
| SCHEMBL23111242 | 0.88 | SLC8A1 (0.41) | ITGB1ITGA4GPR119SLC8A1GRIN2B | |
| SCHEMBL20601347 | 0.88 | ITGB1 (0.41) | ITGB1ITGA4GPR119SLC8A1MMP13 | |
| SCHEMBL20601345 | 0.88 | ITGB1 (0.41) | ITGB1ITGA4GPR119SLC8A1MMP13 | |
| SCHEMBL20601555 | 0.87 | ITGB1 (0.42) | ITGB1ITGA4GPR119SLC8A1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770222-A | Modulators of indoleamine2, 3-dioxygenase | 葛兰素史克知识产权开发有限公司 | 2020-02-07 | — | — | CN | disclosed |