SCHEMBL28356089

SCHEMBL28356089

c1ccc(-c2cccc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c2-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ATM Q13315 1/20 0.57
KMT2A Q03164 3/20 0.46
HDAC4 P56524 1/20 0.42
MAPK14 Q16539 1/20 0.40
IL1R1 P14778 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
PTPN1 P18031 2/20 0.37
HSD17B10 Q99714 1/20 0.36
HTR6 P50406 2/20 0.36
DUSP3 P51452 1/20 0.36
ENPP1 P22413 1/20 0.36
METAP2 P50579 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EDNRB P24530 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780976 0.96 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL14410401 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL14429630 0.91 L3MBTL1 (0.47) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL24948358 0.89 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL13589041 0.89 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL14429632 0.89 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL16447339 0.89 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL19793270 0.89 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL30007102 0.89 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL24398195 0.89 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106575709-B Charge-transporting material 日产化学工业株式会社 2020-01-07 CN disclosed