Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28356363 | 0.86 | ALDH1A1 (0.61) | ALDH1A1RXFP1POLBKMT2AGLA | |
| SCHEMBL30509768 | 0.86 | ALDH1A1 (0.48) | ALDH1A1RXFP1TAS1R3TAS1R1PPID | |
| SCHEMBL14688152 | 0.85 | ALDH1A1 (0.70) | ALDH1A1RXFP1POLBKMT2AGLA | |
| SCHEMBL28352594 | 0.84 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2AUTS2R | |
| SCHEMBL28356496 | 0.83 | HDAC8 (0.60) | ALDH1A1POLBKMT2A | |
| SCHEMBL20502747 | 0.83 | ALDH1A1 (0.68) | ALDH1A1RXFP1POLBKMT2AGLA | |
| SCHEMBL28356107 | 0.82 | ALDH1A1 (0.67) | ALDH1A1RXFP1POLBKMT2AGLA | |
| SCHEMBL28352797 | 0.82 | ALDH1A1 (0.56) | ALDH1A1RXFP1TAS1R3TAS1R1PPID | |
| SCHEMBL4403600 | 0.81 | ALDH1A1 (0.55) | ALDH1A1RXFP1POLBKMT2AGLA | |
| SCHEMBL16773392 | 0.81 | ALDH1A1 (0.55) | ALDH1A1RXFP1POLBKMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770209-B | Novel 5-hydroxypyridine compounds useful as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2023-06-30 | — | — | CN | disclosed |
| CN-110770209-A | Novel 5-hydroxypyridines as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2020-02-07 | — | — | CN | disclosed |