Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352780 | 0.89 | MAOB (0.42) | MAOBDAOCALCRLMMP13PGR | |
| SCHEMBL28356605 | 0.89 | OPRM1 (0.39) | MAOBKCNH2 | |
| SCHEMBL28356460 | 0.82 | MAOB (0.40) | MAOBB3GNT2 | |
| SCHEMBL24117151 | 0.80 | OPRM1 (0.39) | KCNH2 | |
| SCHEMBL28352781 | 0.79 | SCN9A (0.50) | MAOB | |
| SCHEMBL28356584 | 0.78 | TRIM24 (0.38) | S1PR2PARG | |
| SCHEMBL24117016 | 0.72 | AURKA (0.38) | DAOPGRPARG | |
| SCHEMBL20278180 | 0.71 | CYP2D6 (0.41) | KCNH2S1PR2 | |
| SCHEMBL24116800 | 0.71 | MAOB (0.46) | MAOBHSD17B10 | |
| SCHEMBL18638354 | 0.69 | PDE4A (0.33) | MMP13S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612290-A | Novel benzimidazolone compounds and medicinal use thereof | 大日本住友制药株式会社 | 2019-12-24 | — | — | CN | claimed |
| CN-110612290-A | Novel benzimidazolone compounds and medicinal use thereof | 大日本住友制药株式会社 | 2019-12-24 | — | — | CN | disclosed |