SCHEMBL28356397

SCHEMBL28356397

Cc1c(CC(=O)OCOC(=O)C(C)C)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20508235 0.92 PTGDR2 (0.81) PTGDR2
SCHEMBL28356388 0.91 PTGDR2 (0.74) PTGDR2
SCHEMBL1940778 0.89 PTGDR2 (0.82) PTGDR2
SCHEMBL28356617 0.88 PTGDR2 (0.74) PTGDR2
SCHEMBL28352679 0.87 PTGDR2 (0.73) PTGDR2
Fevipiprant SCHEMBL29355753 0.87 PTGDR2 (1.00) PTGDR2
Fevipiprant SCHEMBL1940595 0.87 PTGDR2 (1.00) PTGDR2
SCHEMBL21591931 0.84 PTGDR2 (0.82) PTGDR2
SCHEMBL21913728 0.83 PTGDR2 (0.72) PTGDR2
SCHEMBL1940440 0.82 PTGDR2 (0.82) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110759906-A Prodrug of Fevipiprant and preparation method and application thereof 重庆美普蓝科技有限公司 2020-02-07 CN disclosed