Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA6 | P23280 | 2/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.65 |
| ▸ | ITGAL | P20701 | 1/20 | 0.65 |
| ▸ | ADK | P55263 | 1/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL20819817 | 0.86 | AHR (0.74) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL11402854 | 0.84 | AHR (0.77) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL345395 | 0.82 | AHR (0.74) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL21723436 | 0.82 | AHR (0.74) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL27679207 | 0.82 | AHR (0.74) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL30042337 | 0.82 | AHR (0.74) | AHRCA1CA4CA6TRPA1 | |
| Indole SCHEMBL30250492 | 0.81 | — | — | |
| Indole SCHEMBL29352896 | 0.81 | — | — | |
| Indole SCHEMBL30463845 | 0.81 | — | — | |
| Indole SCHEMBL1160186 | 0.81 | AHR (1.00) | AHRCA1CA4CA6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603188-A | Indole and quinoline skeleton-containing compound and application thereof | 苏州卫生职业技术学院 | 2024-02-27 | — | — | CN | claimed |
| CN-114591295-B | Pyridine salt-containing N- (indolyl) -N' - (substituted) propyl hydrazide derivative, preparation method and application thereof | 贵州大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114591295-A | Pyridine salt-containing N- (indoleacyl) -N' - (substituted) propyl hydrazide derivative, and preparation method and application thereof | 贵州大学 | 2022-06-07 | — | — | CN | claimed |
| CN-107235966-B | A kind of bis- indoles -1,2,4- triazole ketone compounds of 3,4- and its preparation method and application | 浙江工业大学 | 2019-12-03 | — | — | CN | claimed |
| CN-107235966-A | Triazole ketone compounds of one indoles of class 3,4 pairs 1,2,4 and its preparation method and application | 浙江工业大学 | 2017-10-10 | — | — | CN | claimed |
| CN-117603188-A | Indole and quinoline skeleton-containing compound and application thereof | 苏州卫生职业技术学院 | 2024-02-27 | — | — | CN | disclosed |
| CN-113278020-B | Pityriacitrin alkaloid derivative containing acylthiourea structure and preparation method and application thereof | 河北工业大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-113444087-B | Pityriacitrin alkaloid derivative containing acylhydrazone structure and preparation method and application thereof | 河北工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-114478537-A | Cyclic amide-fused ring compound and medical use thereof | 上海拓界生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-110759913-B | Indolylhydrazone derivatives, preparation method thereof and application thereof in plant virus prevention and control, sterilization and disinsection | 南开大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113444087-A | Pityriacitrin alkaloid derivative containing acylhydrazone structure and preparation method and application thereof | 河北工业大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-113278020-A | Pityriacitrin alkaloid derivative containing acylthiourea structure and preparation method and application thereof | 河北工业大学 | 2021-08-20 | — | — | CN | disclosed |
| CN-110759913-A | Indolylhydrazone derivatives, preparation method thereof and application thereof in plant virus prevention and control, sterilization and disinsection | 南开大学 | 2020-02-07 | — | — | CN | disclosed |
| CN-107235966-B | A kind of bis- indoles -1,2,4- triazole ketone compounds of 3,4- and its preparation method and application | 浙江工业大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-107235966-B | A kind of bis- indoles -1,2,4- triazole ketone compounds of 3,4- and its preparation method and application | 浙江工业大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-107235966-A | Triazole ketone compounds of one indoles of class 3,4 pairs 1,2,4 and its preparation method and application | 浙江工业大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-107235966-A | Triazole ketone compounds of one indoles of class 3,4 pairs 1,2,4 and its preparation method and application | 浙江工业大学 | 2017-10-10 | — | — | CN | disclosed |