SCHEMBL28357015

SCHEMBL28357015

CC(=O)NC(C)(Cl)CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 2/20 0.42
HMGCR P04035 1/20 0.42
CHRM1 P11229 1/20 0.42
TBXA2R P21731 1/20 0.42
HIF1A Q16665 3/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 3/20 0.37
CPT2 P23786 2/20 0.37
FFAR1 O14842 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NAALAD2 Q9Y3Q0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KDM4C Q9H3R0 1/20 0.31
EPHX1 P07099 1/20 0.31
MAPK1 P28482 1/20 0.31
PKM P14618 1/20 0.31
ACLY P53396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371858 0.76 ADRA1A (0.46) ADRA1AHMGCRCHRM1TBXA2RHIF1A
SCHEMBL27803196 0.75 MEN1 (0.42) ADRA1AHMGCRCHRM1TBXA2RHIF1A
SCHEMBL27803195 0.75 MEN1 (0.42) ADRA1AHMGCRCHRM1TBXA2RHIF1A
SCHEMBL10866277 0.71 ADRA1A (0.41) ADRA1AHMGCRCHRM1TBXA2RHIF1A
SCHEMBL27474939 0.69
SCHEMBL1131819 0.69
SCHEMBL451570 0.69
SCHEMBL1132145 0.69
Acetone SCHEMBL1591738 0.67 HMGCR (0.46) ADRA1AHMGCRCHRM1TBXA2RHIF1A
Acetic Acid SCHEMBL1591292 0.67 HMGCR (0.46) ADRA1AHMGCRCHRM1TBXA2RHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642736-A Synthesis method of acetamido-3-methyl chloropropionate 湖北宇阳药业有限公司 2020-01-03 CN claimed
CN-110642736-A Synthesis method of acetamido-3-methyl chloropropionate 湖北宇阳药业有限公司 2020-01-03 CN disclosed
CN-110642736-A Synthesis method of acetamido-3-methyl chloropropionate 湖北宇阳药业有限公司 2020-01-03 CN disclosed
CN-110642736-A Synthesis method of acetamido-3-methyl chloropropionate 湖北宇阳药业有限公司 2020-01-03 CN disclosed