Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29023619 | 0.79 | IDO1 (0.40) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL6042735 | 0.78 | IDO1 (0.43) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL11231017 | 0.74 | ACP3 (0.46) | IDO1MEN1KMT2ATDP1MAPT | |
| SCHEMBL1616038 | 0.73 | GRIN2D (0.47) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL27820610 | 0.72 | TSHR (0.53) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL1795446 | 0.71 | CYP3A4 (0.48) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL19069697 | 0.70 | HTT (0.48) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL11126521 | 0.70 | IDO1 (0.48) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL1793817 | 0.70 | MAPT (0.52) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL21192748 | 0.70 | IDO1 (0.48) | IDO1MEN1KMT2ATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089639-A1 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | NOVARTIS AG (CH) | 2022-03-24 | — | — | US | disclosed |
| CN-105593238-B | Lysine-specific chemoenzymatic protein modification using microbial transglutaminase | 诺华股份有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-110770243-A | Rapamycin analogs as MTOR inhibitors | 锐新医药公司 | 2020-02-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089639-A1 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | PTMS, TGM3, TGM1 | IDO1 804/4885MEN1 2255/4885KMT2A 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.