Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31292996 | 1.00 | HTR2C (0.46) | HTR2CKDM4ELMNAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL31293257 | 0.98 | HTR2C (0.45) | HTR2CKDM4ELMNAGAAMEN1 | |
| SCHEMBL27210132 | 0.81 | HTR2C (0.46) | HTR2CMAPK10HTR2A | |
| SCHEMBL30477973 | 0.81 | KDM4E (0.48) | HTR2CKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL28172745 | 0.81 | KDM4E (0.48) | HTR2CKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL30921653 | 0.78 | KDM4E (0.58) | HTR2CKDM4ELMNAGAAMEN1 | |
| SCHEMBL28631444 | 0.78 | KDM4E (0.58) | HTR2CKDM4ELMNAGAAMEN1 | |
| SCHEMBL678673 | 0.77 | HTR2C (0.54) | HTR2CKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL15101404 | 0.73 | KDM4E (0.54) | HTR2CKDM4ELMNAGAAMEN1 | |
| SCHEMBL1655707 | 0.70 | KDM4E (0.52) | HTR2CKDM4ELMNAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141288-B | Evodiamine compounds and preparation method and application thereof | 中山大学 | 2019-12-27 | — | — | CN | disclosed |