Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP16 | Q8N5Y8 | 2/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569434 | 0.84 | CRBN (0.53) | DDB1CRBNALDH1A1NPC1MAPT | |
| SCHEMBL29967570 | 0.83 | CRBN (0.56) | MTNR1ADDB1CRBNALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL29968157 | 0.81 | CRBN (0.55) | MTNR1ADDB1CRBNALDH1A1NPC1 | |
| SCHEMBL9194941 | 0.77 | MTNR1A (0.46) | MTNR1AALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL445499 | 0.77 | MAPT (0.50) | DDB1CRBNALDH1A1NPC1MAPT | |
| SCHEMBL8271400 | 0.75 | MTNR1A (0.38) | MTNR1AALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL7897281 | 0.75 | CHRNB4 (0.45) | DDB1CRBNALDH1A1NPC1MAPT | |
| SCHEMBL24366930 | 0.75 | PDE4A (0.40) | MTNR1AALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL23264002 | 0.75 | MTNR1A (0.39) | MTNR1ADDB1CRBNALDH1A1PDE4A | |
| SCHEMBL7568818 | 0.74 | MAPT (0.52) | DDB1CRBNALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143179-B1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-22 | — | — | EP | claimed |
| US-20230174514-A1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-06-08 | — | — | US | disclosed |
| CN-110804061-B | Pyrazole and pyrazine formamide compound containing cyclopropyl segment and application thereof | 中国医学科学院医药生物技术研究所 | 2021-01-05 | — | — | CN | disclosed |
| CN-110804061-A | Pyrazole and pyrazine formamide compound containing cyclopropyl segment and application thereof | 中国医学科学院医药生物技术研究所 | 2020-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174514-A1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS | CCR6, CCR1, CCR3 | MTNR1A 216/4885DDB1 2086/4885CRBN 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.