Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | CD74 | P04233 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073980 | 0.87 | MEN1 (0.48) | MEN1GAAKMT2APOLBHPGD | |
| SCHEMBL30339031 | 0.87 | MEN1 (0.48) | MEN1GAAKMT2APOLBHPGD | |
| SCHEMBL25063109 | 0.86 | CNR2 (0.47) | ELANEHTR1AHTR7HPGDTSHR | |
| SCHEMBL28357440 | 0.83 | TNFRSF1A (0.45) | ELANENQO1MEN1GAAKMT2A | |
| SCHEMBL28357308 | 0.83 | MIF (0.54) | MIFCD74PLA2G2APOLB | |
| SCHEMBL28357125 | 0.83 | ELANE (0.41) | ELANENQO1MEN1GAAKMT2A | |
| SCHEMBL28357203 | 0.81 | KMT2A (0.49) | MEN1KMT2AMIFCD74PLA2G2A | |
| SCHEMBL15991573 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AMIFCD74MAOA | |
| SCHEMBL24074349 | 0.80 | ELANE (0.41) | ELANEKMT2APOLBUSP2HPGD | |
| SCHEMBL9790070 | 0.80 | ELANE (0.48) | ELANENQO1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141288-B | Evodiamine compounds and preparation method and application thereof | 中山大学 | 2019-12-27 | — | — | CN | disclosed |