Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357807 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28357917 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361581 | 0.85 | MTNR1A (0.43) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361551 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28357913 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361545 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361582 | 0.85 | MTNR1A (0.43) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28358031 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28358035 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28357901 | 0.83 | MTNR1A (0.39) | MTNR1AMTNR1BABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818720-A | Melatonin (MT1/MT2) receptor agonist, preparation method and application thereof | 上海阳帆医药科技有限公司 | 2020-02-21 | — | — | CN | disclosed |