Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170957 | 0.81 | CA1 (0.40) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL3871490 | 0.81 | ALDH1A1 (0.37) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL15102770 | 0.81 | MAPT (0.38) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL1350658 | 0.81 | ALDH1A1 (0.37) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL30292674 | 0.81 | MAPT (0.38) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL2705849 | 0.79 | ALDH1A1 (0.48) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL8914013 | 0.79 | ALDH1A1 (0.48) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL1296897 | 0.79 | ALDH1A1 (0.48) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL2705851 | 0.79 | ALDH1A1 (0.48) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL12943060 | 0.79 | ALDH1A1 (0.48) | CA1CA2CA12CA9PPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804016-A | Diaryl quinoline derivatives against mycobacterium tuberculosis | 福建省微生物研究所 | 2020-02-18 | — | — | CN | claimed |
| CN-110804016-B | Diaryl quinoline derivatives against mycobacterium tuberculosis | 福建省微生物研究所 | 2022-11-04 | — | — | CN | disclosed |
| CN-110804016-A | Diaryl quinoline derivatives against mycobacterium tuberculosis | 福建省微生物研究所 | 2020-02-18 | — | — | CN | disclosed |