Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358332 | 0.87 | TSHR (0.56) | TSHRHPGDHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL18014862 | 0.78 | HCAR2 (0.42) | HPGDHSD17B10MAPK1ESR2LMNA | |
| SCHEMBL11917921 | 0.78 | — | — | |
| SCHEMBL1935586 | 0.78 | — | — | |
| SCHEMBL6980753 | 0.78 | — | — | |
| SCHEMBL9655871 | 0.77 | TDP1 (0.44) | TSHRHSD17B10ALDH1A1CYP3A4ABL1 | |
| Acrylic Acid Ethyl Ester SCHEMBL4449784 | 0.77 | TSHR (0.43) | TSHRHPGDHSD17B10MAPK1NPSR1 | |
| SCHEMBL8624649 | 0.75 | IRAK4 (0.40) | IRAK4 | |
| Methacrylic Acid SCHEMBL11888730 | 0.74 | ITGB1 (0.38) | TSHRLMNAIRAK4 | |
| SCHEMBL3745667 | 0.74 | CYP1A2 (0.44) | TSHRHSD17B10MAPK1LMNAIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746354-B | Acrylate compound, preparation method and application | 山东瑞博龙化工科技股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-110746354-A | Acrylate compound, preparation method and application | 山东瑞博龙化工科技股份有限公司 | 2020-02-04 | — | — | CN | disclosed |