Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 4/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 4/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372330 | 0.84 | ALDH1A1 (0.40) | TDP1ALDH1A1ALOX15USP2TSHR | |
| SCHEMBL26508624 | 0.82 | NLRP3 (0.47) | DGKA | |
| SCHEMBL26508641 | 0.82 | NLRP3 (0.47) | DGKA | |
| SCHEMBL3745667 | 0.80 | CYP1A2 (0.44) | TDP1ALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL1935586 | 0.78 | — | — | |
| SCHEMBL11917921 | 0.78 | — | — | |
| SCHEMBL6980753 | 0.78 | — | — | |
| SCHEMBL8624649 | 0.75 | IRAK4 (0.40) | — | |
| SCHEMBL495925 | 0.72 | CYP1A2 (0.70) | TDP1ALDH1A1ALOX15USP2TSHR | |
| SCHEMBL6055406 | 0.72 | CYP1A2 (0.70) | TDP1ALDH1A1ALOX15USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082663-A | EXTERNAL ADHESIVE PREPARATION CONTAINING STEROIDS | TEIKOKU SEIYAKY CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0280737-B1 | STEROIDAL DRUG-CONTAINING PREPARATION FOR EXTERNAL USE | TEIKOKU SEIYAKU CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0280737-A1 | STEROIDAL DRUG-CONTAINING PREPARATION FOR EXTERNAL USE | TEIKOKU SEIYAKU CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |