SCHEMBL28358205

SCHEMBL28358205

N#Cc1cnc(-c2cccs2)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.44
KDR P35968 1/20 0.44
ADORA2A P29274 3/20 0.43
ADORA1 P30542 2/20 0.43
ADORA2B P29275 1/20 0.43
MAOA P21397 2/20 0.42
MAOB P27338 1/20 0.42
ALDH1A1 P00352 4/20 0.40
TDO2 P48775 1/20 0.40
FOS P01100 1/20 0.40
JUN P05412 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RPS6KB2 Q9UBS0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031032 0.75 CSNK2A1 (0.41) CDK1KDRADORA2AADORA1ADORA2B
SCHEMBL10783915 0.75 ADORA2A (0.56) CDK1KDRADORA2AADORA1ALDH1A1
SCHEMBL6440667 0.74 ADORA2A (0.59) CDK1KDRADORA2AADORA1ADORA2B
SCHEMBL31674375 0.74 PIK3CD (0.40) ADORA2AADORA1KMT2AMAPT
SCHEMBL3291066 0.72 CYP11B1 (0.43) CDK1KDRADORA2AADORA1ADORA2B
SCHEMBL2980649 0.71 CYP1A2 (0.49) CDK1KDRADORA2AADORA1ADORA2B
SCHEMBL2981824 0.69 CDK1 (0.47) CDK1KDRADORA2AADORA1ADORA2B
SCHEMBL2710842 0.69 ALDH1A1 (0.43) ADORA2AADORA1ALDH1A1KMT2AMEN1
SCHEMBL1028588 0.68 MAPT (0.45) ADORA2AADORA1ADORA2BMAOAMAOB
SCHEMBL11937877 0.68 ADORA2A (0.41) CDK1KDRADORA2AADORA1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818740-B Iridium complex as near-infrared luminescent material and application thereof 五邑大学 2022-05-03 CN disclosed
CN-110818740-A Iridium complex as near-infrared luminescent material and application thereof 五邑大学 2020-02-21 CN disclosed