Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL28678428 | 0.97 | TP53 (0.44) | TP53 | |
| Diethylamine SCHEMBL27878566 | 0.80 | — | — | |
| Cyclohexane SCHEMBL10983411 | 0.80 | TP53 (0.73) | TP53MEN1GLACYP2C19KMT2A | |
| Diethylamine SCHEMBL4083176 | 0.77 | — | — | |
| Propane SCHEMBL3672248 | 0.77 | — | — | |
| Dimethylamine SCHEMBL28362007 | 0.74 | — | — | |
| SCHEMBL1494542 | 0.73 | — | — | |
| SCHEMBL8388128 | 0.73 | — | — | |
| SCHEMBL8383685 | 0.73 | — | — | |
| SCHEMBL4134535 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226599-B | Recycling treatment method of iron-containing heavy metal sludge | 环境保护部南京环境科学研究所 | 2020-02-21 | — | — | CN | disclosed |