Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354844 | 0.84 | KMT2A (0.66) | LMNASMN1; SMN2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28019227 | 0.83 | GFER (0.49) | LMNASMN1; SMN2GFERGAACYP2C9 | |
| SCHEMBL13935791 | 0.83 | GFER (0.74) | LMNASMN1; SMN2GFERGAACYP2C9 | |
| SCHEMBL3675077 | 0.82 | GFER (0.57) | LMNASMN1; SMN2GFERGAAMEN1 | |
| SCHEMBL28004406 | 0.82 | KMT2A (0.69) | SMN1; SMN2GFERGAAMEN1KMT2A | |
| SCHEMBL3709112 | 0.80 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2GFERGAACYP2C9 | |
| SCHEMBL12300199 | 0.79 | PRKCI (0.67) | LMNASMN1; SMN2GFERGAAMEN1 | |
| SCHEMBL6992077 | 0.78 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2GFERGAAMEN1 | |
| SCHEMBL27476499 | 0.78 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2GFERGAAMEN1 | |
| SCHEMBL28149380 | 0.77 | GFER (0.56) | LMNASMN1; SMN2GFERGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713458-B | N- (2-benzoylaminoethyl) -2-chloronicotinamide compound and preparation method and application thereof | 浙江工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-110713458-A | N- (2-benzoylaminoethyl) -2-chloronicotinamide compound and preparation method and application thereof | 浙江工业大学 | 2020-01-21 | — | — | CN | disclosed |