Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044446 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4ETSHRHTT | |
| SCHEMBL15214378 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EPOLBLMNA | |
| SCHEMBL13381564 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EHTTPOLB | |
| SCHEMBL30701070 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4ETSHRHTT | |
| SCHEMBL17961787 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4ETSHRHTT | |
| SCHEMBL22656819 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10KDM4ETSHRHTT | |
| SCHEMBL11999087 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4EPOLBLMNA | |
| SCHEMBL28033665 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL29441612 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL11213802 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624981-B | Preparation method of 2-fluoro-5- [ (4-oxo-3H-2, 3-diazanaphthyl) methyl ] benzoic acid | 南京桦冠生物技术有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-112624981-A | Preparation method of 2-fluoro-5- [ (4-oxo-3H-2, 3-diazanaphthyl) methyl ] benzoic acid | 南京桦冠生物技术有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-110790710-A | Synthetic method of olaparib | 东南大学 | 2020-02-14 | — | — | CN | claimed |
| CN-117229219-A | Preparation method of high-purity olapari | 合肥创新医药技术有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117229219-A | Preparation method of high-purity olapari | 合肥创新医药技术有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-112624981-B | Preparation method of 2-fluoro-5- [ (4-oxo-3H-2, 3-diazanaphthyl) methyl ] benzoic acid | 南京桦冠生物技术有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-112624981-B | Preparation method of 2-fluoro-5- [ (4-oxo-3H-2, 3-diazanaphthyl) methyl ] benzoic acid | 南京桦冠生物技术有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-112661733-A | Olapari impurity intermediate, Olapari impurity and preparation method thereof | 南京方生和医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-112624981-A | Preparation method of 2-fluoro-5- [ (4-oxo-3H-2, 3-diazanaphthyl) methyl ] benzoic acid | 南京桦冠生物技术有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-112624981-A | Preparation method of 2-fluoro-5- [ (4-oxo-3H-2, 3-diazanaphthyl) methyl ] benzoic acid | 南京桦冠生物技术有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-108794405-B | Method for continuously preparing Olaparib intermediate by adopting micro-channel modular reaction device | 南京工业大学 | 2020-09-04 | — | — | CN | disclosed |
| CN-110790710-A | Synthetic method of olaparib | 东南大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110790710-A | Synthetic method of olaparib | 东南大学 | 2020-02-14 | — | — | CN | disclosed |