SCHEMBL28358741

SCHEMBL28358741

CCCCc1ccc(C(C)(C)CC)cc1O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.59
MEN1 O00255 1/20 0.51
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51
ALOX5 P09917 1/20 0.51
MAPT P10636 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
CNR1 P21554 11/20 0.43
CNR2 P34972 11/20 0.43
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269961 0.87 ESR1 (0.53) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL29636487 0.86 TYR (0.62) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL5168560 0.86 TYR (0.62) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL9797614 0.81 TYR (0.61) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL11800133 0.80 TYR (0.65) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL28371146 0.80 TYR (0.54) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL8707610 0.78 TYR (0.56) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL340143 0.76 NPC1 (0.55) ALOX15TDP1CNR1CNR2ESR1
SCHEMBL56223 0.76 ALDH1A1 (0.61) ALOX15TDP1CNR1CNR2ESR1
SCHEMBL27997840 0.75 ESR1 (0.55) TYRCYP3A4CNR1CNR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869460-A Heat transfer compositions, methods, and systems 霍尼韦尔国际公司 2020-03-06 CN disclosed