Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21676975 | 0.79 | HTR2A (0.31) | HTR2AHRH1 | |
| SCHEMBL19630929 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL3677946 | 0.72 | MAPK1 (0.36) | HTR2AHRH1 | |
| SCHEMBL23393773 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL21351791 | 0.71 | — | — | |
| SCHEMBL12128465 | 0.70 | — | — | |
| SCHEMBL12210679 | 0.70 | — | — | |
| SCHEMBL14727510 | 0.69 | — | — | |
| SCHEMBL12125666 | 0.69 | HTR2A (0.33) | HTR2AHRH1 | |
| SCHEMBL21729979 | 0.69 | HTR2A (0.33) | SLC6A4HRH3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831584-B | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-110831584-A | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2020-02-21 | — | — | CN | disclosed |