Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29108787 | 0.80 | HTR2A (0.43) | HTR2AMAPTMEN1NPC1GAA | |
| SCHEMBL22555840 | 0.78 | CDK4 (0.47) | HTR2AMAPTMEN1NPC1GAA | |
| SCHEMBL734207 | 0.71 | HTR2A (0.52) | HTR2AMAPTMEN1NPC1GAA | |
| SCHEMBL4985934 | 0.69 | HTR2A (0.77) | HTR2AMAPTMEN1KMT2AHTR1A | |
| SCHEMBL29188240 | 0.69 | HTR2A (0.64) | HTR2AMAPTMEN1NPC1GAA | |
| SCHEMBL104310 | 0.69 | HTR2A (0.61) | HTR2AMAPTMEN1KMT2AHTR1A | |
| SCHEMBL734407 | 0.69 | HTR2A (0.52) | HTR2AMAPTMEN1NPC1GAA | |
| SCHEMBL1781382 | 0.68 | GPR18 (0.51) | HTR2AMAPTMEN1NPC1GAA | |
| SCHEMBL24746493 | 0.68 | HTR2A (0.70) | HTR2AHTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL6465788 | 0.68 | HTR2A (0.88) | HTR2ARAB9AHTR1AHTR6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-110831600-A | Indole AHR inhibitors and uses thereof | 金恩医疗公司 | 2020-02-21 | — | — | CN | disclosed |