Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652597 | 0.93 | VCP (0.69) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL28745823 | 0.89 | APP (0.56) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL978641 | 0.86 | VCP (0.75) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL13077510 | 0.83 | APP (0.69) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL28972921 | 0.82 | GPR183 (0.51) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL10625119 | 0.82 | VCP (0.81) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL28542054 | 0.81 | VCP (0.59) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL16582689 | 0.81 | VCP (0.86) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL10070193 | 0.81 | VCP (0.58) | VCPHSP90AA1MAPTALDH1A1KMT2A | |
| SCHEMBL30055393 | 0.81 | HSP90AA1 (0.60) | VCPHSP90AA1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-06-12 | — | — | US | disclosed |
| CN-116354914-B | Triphenylsubstituted pyrone derivative and synthetic method and application thereof | 河南科技大学 | 2024-09-03 | — | — | CN | disclosed |
| EP-4333819-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | Katholieke Universiteit Leuven (BE) | 2024-03-13 | — | — | EP | disclosed |
| CN-116354914-A | Triphenylsubstituted pyrone derivative and synthetic method and application thereof | 河南科技大学 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022233877-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-11-10 | — | — | WO | disclosed |
| CN-110627626-B | Preparation method of propargyl acetone compound | 内蒙古大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-108148064-B | Method for preparing pyrazole quinoxalinone derivative | 浙江百斯特化工有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-110627626-A | Preparation method of propargyl acetone compound | 内蒙古大学 | 2019-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | CNR1, CNR2, CYP2J2 | VCP 4323/4885HSP90AA1 3775/4885MAPT 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.