Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214627 | 0.88 | PTPN11 (0.54) | PTPN11S1PR3PTPN1PTPN6ALDH1A1 | |
| SCHEMBL1747598 | 0.88 | PTPN11 (0.53) | PTPN11S1PR3PTPN1PTPN6MEN1 | |
| SCHEMBL27558746 | 0.87 | PTPN11 (0.56) | PTPN11S1PR3PTPN1PTPN6ALDH1A1 | |
| SCHEMBL27579133 | 0.87 | PTPN11 (0.56) | PTPN11S1PR3PTPN1PTPN6ALDH1A1 | |
| SCHEMBL28214715 | 0.86 | LMNA (0.60) | PTPN11S1PR3PTPN1ALDH1A1TSHR | |
| SCHEMBL9153749 | 0.86 | LMNA (0.60) | PTPN11S1PR3PTPN1ALDH1A1TSHR | |
| SCHEMBL5722029 | 0.86 | LMNA (0.60) | PTPN11S1PR3PTPN1ALDH1A1TSHR | |
| SCHEMBL8461191 | 0.85 | PTPN11 (0.52) | PTPN11S1PR3PTPN1PTPN6ALDH1A1 | |
| SCHEMBL8085939 | 0.84 | MEN1 (0.57) | PTPN11S1PR3PTPN1MEN1NR1I2 | |
| SCHEMBL8462893 | 0.84 | PTPN11 (0.51) | PTPN11S1PR3PTPN1PTPN6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105979977-B | Support frame | 牛津大学科技创新有限公司 | 2020-03-10 | — | — | CN | disclosed |