Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28442298 | 0.90 | FOLH1 (0.51) | FOLH1TSHRALDH1A1ALOX15SLC16A3 | |
| SCHEMBL6445972 | 0.84 | FOLH1 (0.59) | FOLH1TSHRALDH1A1ALOX15SLC16A3 | |
| SCHEMBL28434886 | 0.83 | FOLH1 (0.49) | FOLH1TSHRALDH1A1ALOX15CLCN2 | |
| SCHEMBL27965407 | 0.83 | FOLH1 (0.58) | FOLH1TSHRALDH1A1ALOX15SLC16A3 | |
| Phthalic Acid SCHEMBL30288540 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15HMGB1 | |
| Phthalic Acid SCHEMBL6551340 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15HMGB1 | |
| Phthalic Acid SCHEMBL11274547 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15HMGB1 | |
| SCHEMBL11228089 | 0.79 | FOLH1 (0.53) | FOLH1TSHRALDH1A1ALOX15SLC16A3 | |
| SCHEMBL28432338 | 0.79 | FOLH1 (0.45) | FOLH1TSHRALDH1A1ALOX15SLC16A3 | |
| SCHEMBL30365583 | 0.78 | FOLH1 (0.76) | FOLH1TSHRALDH1A1ALOX15SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448182-A | Aztreonam derivative and application thereof | 阿里萨制药有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-110662746-A | Prodrugs of 3- ((((((2S,5R) -2-carbamoyl-7-oxo-1, 6-diazabicyclo [3.2.1] oct-6-yl) oxy) sulfonyl) oxy) -2, 2-dimethylpropionate derivatives and related compounds for oral administration as beta-lactamase inhibitors for treating bacterial infections | 阿里萨制药有限公司 | 2020-01-07 | — | — | CN | disclosed |