Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359771 | 1.00 | CASP3 (0.62) | CASP3PTPN1TLR2KMT2AMDM4 | |
| SCHEMBL14610886 | 0.96 | CASP3 (0.59) | CASP3PTPN1TLR2KMT2AMDM4 | |
| SCHEMBL29431036 | 0.91 | CASP3 (0.53) | CASP3PTPN1TLR2KMT2AMDM4 | |
| SCHEMBL13462127 | 0.91 | CASP3 (0.59) | CASP3PTPN1TLR2KMT2AMDM4 | |
| SCHEMBL31317732 | 0.90 | CASP3 (0.60) | CASP3TLR2KMT2AMDM4TP53 | |
| SCHEMBL29709561 | 0.90 | CASP3 (0.70) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL31560034 | 0.90 | PTPN1 (0.53) | CASP3PTPN1TLR2KMT2AMDM4 | |
| SCHEMBL29412684 | 0.90 | PTPN1 (0.53) | CASP3PTPN1TLR2KMT2AMDM4 | |
| SCHEMBL21713266 | 0.89 | CASP3 (0.56) | CASP3PTPN1KMT2AMDM4TP53 | |
| SCHEMBL21713268 | 0.89 | CASP3 (0.56) | CASP3PTPN1KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831633-A | Peptide linker and cryptophycin conjugate for therapy and preparation thereof | 赛诺菲 | 2020-02-21 | — | — | CN | disclosed |