Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164941 | 0.81 | AOC3 (1.00) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL1793814 | 0.81 | AOC3 (1.00) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| Hydrazine SCHEMBL28353884 | 0.79 | AOC3 (0.95) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4696173 | 0.79 | AOC3 (0.95) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11186055 | 0.79 | AOC3 (0.95) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL28459179 | 0.79 | AOC3 (0.95) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| Bromide SCHEMBL28239009 | 0.77 | AOC3 (0.91) | AOC3ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL28765479 | 0.71 | TSHR (0.47) | AOC3ALDH1A1TSHRCARM1PRMT6 | |
| SCHEMBL11750385 | 0.70 | AOC3 (0.75) | AOC3ALDH1A1TSHRCARM1PRMT6 | |
| SCHEMBL12124877 | 0.70 | TSHR (0.50) | AOC3ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015396-A | Compositions and methods for treating cancer with chimeric TIM receptors in combination with poly (ADP-ribose) polymerase inhibitors | 森罗治疗公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116390936-A | Chimeric TIM receptors and uses thereof | 森罗治疗公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-112867512-A | Combination therapy | 意大利国际先进加速器应用有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-107667092-B | Formylated N-heterocyclic derivatives as FGFR4 inhibitors | 诺华股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112584901-A | Methods and compositions for blocking interactions between non-glycosylated PD-1 polypeptides | 真和制药有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-112218886-A | Expression vector of chimeric phagocytic receptor, genetically modified host cell and application thereof | 森罗治疗公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112218887-A | Cellular immunotherapy compositions and uses thereof | 森罗治疗公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112218651-A | Immunopotentiating RNA for combination with chimeric antigen receptor therapy | 诺华公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-111770759-A | Targeting the CBM-signalosome complex to induce regulatory T cells to inflame the tumor microenvironment | 通用医疗公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-111386284-A | Chimeric phagocytic receptor molecules and methods of use | 森罗治疗公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-110799640-A | T cells expressing chimeric antigen receptors | 综合医院公司 | 2020-02-14 | — | — | CN | disclosed |