SCHEMBL1164941

SCHEMBL1164941

CN(N)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AOC3 Q16853 3/20 1.00
▸ TSHR P16473 3/20 0.64
▸ ALDH1A1 P00352 2/20 0.64
▸ CARM1 Q86X55 1/20 0.56
▸ PRMT6 Q96LA8 1/20 0.56
▸ PRMT8 Q9NR22 1/20 0.56
▸ NPC1 O15118 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ LMNA P02545 2/20 0.48
▸ CA12 O43570 2/20 0.48
▸ CA9 Q16790 2/20 0.48
▸ ADRA2B P18089 1/20 0.48
▸ ADRA2C P18825 1/20 0.48
▸ SLC6A2 P23975 1/20 0.48
▸ HTR2A P28223 1/20 0.48
▸ SLC6A4 P31645 1/20 0.48
▸ ADRA1A P35348 1/20 0.48
▸ OPRK1 P41145 1/20 0.48
▸ SLC6A3 Q01959 1/20 0.48
▸ KCNH2 Q12809 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1793814 1.00 AOC3 (1.00) AOC3TSHRALDH1A1CARM1PRMT6
Hydrochloric Acid SCHEMBL4696173 0.97 AOC3 (0.95) AOC3TSHRALDH1A1CARM1PRMT6
Ammonia Solution, Strong SCHEMBL28459179 0.97 AOC3 (0.95) AOC3TSHRALDH1A1CARM1PRMT6
Hydrochloric Acid SCHEMBL11186055 0.97 AOC3 (0.95) AOC3TSHRALDH1A1CARM1PRMT6
Hydrazine SCHEMBL28353884 0.97 AOC3 (0.95) AOC3TSHRALDH1A1CARM1PRMT6
Bromide SCHEMBL28239009 0.95 AOC3 (0.91) AOC3TSHRALDH1A1CARM1PRMT6
SCHEMBL11750385 0.86 AOC3 (0.75) AOC3TSHRALDH1A1CARM1PRMT6
SCHEMBL28360424 0.81 AOC3 (0.66) AOC3TSHRALDH1A1CARM1PRMT6
Methylamine SCHEMBL27897983 0.79 ALDH1A1 (0.90) AOC3TSHRALDH1A1CARM1PRMT6
Hydrazine SCHEMBL28104560 0.79 TSHR (0.90) AOC3TSHRALDH1A1CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209439-B Cereblon protein modulators Saint Jude Children's Research Hospital Ltd. (US) 2026-05-26 — — CN claimed
EP-3256420-B1 USE OF MODIFIED AMINES SCALE INHIBITORS IN WET PROCESS PHOSPHORIC ACID PRODUCTION CYTEC IND INC (US) 2025-04-23 — — EP claimed
CN-119677539-A Combination therapy for modulating lipid production 俄亥俄州创新基金会 2025-03-21 — — CN claimed
CN-119546293-A Combination of HDAC inhibitors and statins for the treatment of pancreatic cancer 国家癌症研究所IRCCS-G·帕斯卡莱基金会 2025-02-28 — — CN claimed
CN-119403836-A Methods for eliminating myeloid-derived suppressor cells using NEO-201 antibodies 精密生物制品股份有限公司 2025-02-07 — — CN claimed
CN-114716548-B Anti-FGFR 3 antibodies and uses thereof (株)爱恩德生物 2024-11-05 — — CN claimed
CN-112041343-B Methods and compositions for targeting Treg cells 精密生物制品股份有限公司 2024-08-30 — — CN claimed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 — — CN claimed
CN-113646299-B Novel N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE 2) receptor modulators 梅迪比奥法尔玛公司 2024-07-26 — — CN claimed
CN-118234748-A Methods and compositions for treating hematological malignancies 精密生物制品股份有限公司 2024-06-21 — — CN claimed
CN-1856469-A Fluoro omega-carboxyaryl diphenyl ureas for the treatment and prevention of diseases and disease symptoms BAYER PHARMACEUTICALS CORP (US) 2006-11-01 — — CN claimed
WO-2006014367-A1 FUNCTIONALIZED SILICON COMPOUNDS HONEYWELL INTERNATIONAL INC. (US) 2006-02-09 — — WO claimed
CN-1711076-A Combination cancer therapy of a GST-activated anticancer compound and another anticancer therapy TELIK INC (US) 2005-12-21 — — CN claimed
CN-1646120-A Antineoplastic combinations WYETH CORP (US) 2005-07-27 — — CN claimed
CN-1630516-A Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents UAB RESEARCH FOUNDATION (US) 2005-06-22 — — CN claimed
CN-1496256-A Combinations of epothilone (EPO THIONE) analogs and chemotherapeutic agents for the treatment of proliferative diseases ����˹�ж�-����˹˹������˾ 2004-05-12 — — CN claimed
CN-1088777-A The preparation method that is used for the chemotherapeutic preparation of directly administering to cancer nidus CONG FANZI (CN) 1994-07-06 — — CN claimed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 — — US claimed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 — — EP claimed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 — — EP claimed
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