Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685726 | 0.89 | CA12 (0.39) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL15669149 | 0.84 | CA14 (0.36) | CA14CA12CA1CA7HDAC6 | |
| Hydrochloric Acid SCHEMBL27875284 | 0.82 | CA14 (0.35) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL27421800 | 0.81 | CA14 (0.42) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL22619240 | 0.80 | CA14 (0.41) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL13271767 | 0.79 | CA14 (0.35) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL20485975 | 0.78 | TSHR (0.44) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL11955130 | 0.77 | NAAA (0.38) | CTSK | |
| SCHEMBL1950353 | 0.76 | HDAC6 (0.35) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL2608081 | 0.75 | CA14 (0.49) | CA14CA12CA1CA7HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271203-A | Lipid compounds for gene delivery and lipid nanoparticles comprising the same | 南京星辰智曜生物医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271204-A | Lipid compounds for gene delivery and lipid nanoparticles comprising the same | 南京星辰智曜生物医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117003744-A | Five-membered and six-membered compound, intermediate, preparation method, composition and application | 厦门市博瑞来医药科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-110845474-B | Target I-type PRMT compound and preparation method and application thereof | 四川大学 | 2021-01-12 | — | — | CN | disclosed |
| CN-110845474-A | Target I-type PRMT compound and preparation method and application thereof | 四川大学 | 2020-02-28 | — | — | CN | disclosed |