SCHEMBL28360786

SCHEMBL28360786

CCOC(=O)C[n+]1ccc(-c2ccncc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.49
GAA P10253 1/20 0.45
CDC7 O00311 6/20 0.43
DBF4 Q9UBU7 6/20 0.43
MMP2 P08253 1/20 0.42
MMP13 P45452 1/20 0.42
MMP14 P50281 1/20 0.42
HPGD P15428 4/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CASP1 P29466 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
NFKB1 P19838 1/20 0.41
STAT1 P42224 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28356953 0.98 PPID (0.48) PPIDGAACDC7DBF4MMP2
Hydrochloric Acid SCHEMBL28356951 0.98 PPID (0.48) PPIDGAACDC7DBF4MMP2
Hydrochloric Acid SCHEMBL30008506 0.97 PPID (0.47) PPIDGAACDC7DBF4MMP2
Bromide SCHEMBL9243928 0.89 ALDH1A1 (0.47) GAAHPGDALDH1A1SMN1; SMN2KDM4E
Bromide SCHEMBL16100576 0.82 KMT2A (0.45) PPIDGAAHPGDALDH1A1CASP1
SCHEMBL8971275 0.80 ALDH1A1 (0.45) GAAALDH1A1SMN1; SMN2KDM4E
SCHEMBL21150140 0.78 ALDH1A1 (0.47) GAAALDH1A1HSD17B10SMN1; SMN2KDM4E
SCHEMBL28420286 0.78 CYP2D6 (0.43) GAAHPGDALDH1A1HSD17B10SMN1; SMN2
SCHEMBL22322504 0.78 HDAC1 (0.49) GAAHPGDALDH1A1HSD17B10CASP1
SCHEMBL29019022 0.76 MEN1 (0.46) MMP13HPGDALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642778-B Viologen compound, preparation method and application thereof 淮阴师范学院 2022-10-04 CN disclosed
CN-110642778-A Viologen compound, preparation method and application thereof 淮阴师范学院 2020-01-03 CN disclosed