Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007639 | 0.91 | FDPS (0.41) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL2451018 | 0.73 | FDPS (0.44) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL434034 | 0.73 | FDPS (0.44) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| Pyrimidine SCHEMBL19894136 | 0.70 | FDPS (0.37) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| Pyrimidine SCHEMBL27682816 | 0.70 | FDPS (0.40) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL3697841 | 0.69 | MKNK2 (0.49) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL10726415 | 0.68 | FDPS (0.40) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL28041939 | 0.68 | FDPS (0.40) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL2120550 | 0.68 | FDPS (0.45) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL7102527 | 0.67 | FDPS (0.39) | FDPSLTA4HCYP1A2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642859-B | Pyrimidine thiothiopurine compound and application thereof | 青岛科技大学 | 2021-11-09 | — | — | CN | claimed |
| CN-110642859-A | Pyrimidine thiothiopurine compound and application thereof | 青岛科技大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110642859-B | Pyrimidine thiothiopurine compound and application thereof | 青岛科技大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-110642859-B | Pyrimidine thiothiopurine compound and application thereof | 青岛科技大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-110642859-A | Pyrimidine thiothiopurine compound and application thereof | 青岛科技大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-110642859-A | Pyrimidine thiothiopurine compound and application thereof | 青岛科技大学 | 2020-01-03 | — | — | CN | disclosed |