Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361666 | 1.00 | MTNR1A (0.42) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361576 | 0.87 | MTNR1A (0.44) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361578 | 0.87 | MTNR1A (0.44) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28357902 | 0.82 | MTNR1A (0.39) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28357901 | 0.82 | MTNR1A (0.39) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361554 | 0.79 | MTNR1A (0.38) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361553 | 0.79 | MTNR1A (0.38) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361565 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361564 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL28361560 | 0.70 | MTNR1A (0.47) | MTNR1AMTNR1BABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818720-A | Melatonin (MT1/MT2) receptor agonist, preparation method and application thereof | 上海阳帆医药科技有限公司 | 2020-02-21 | — | — | CN | disclosed |