SCHEMBL28362162

SCHEMBL28362162

C[Si](C)(C)CCCC=O.[MgH2]

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.47
TSHR P16473 2/20 0.46
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 2/20 0.37
HPGD P15428 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815990 0.97
SCHEMBL10787403 0.86 TSHR (0.52) HIF1ATSHRFAAHTRPV1HPGD
SCHEMBL27055257 0.86 TSHR (0.52) HIF1ATSHRFAAHTRPV1HPGD
SCHEMBL12354498 0.86 TSHR (0.52) HIF1ATSHRFAAHTRPV1HPGD
SCHEMBL29109056 0.82
SCHEMBL442304 0.79
SCHEMBL13789644 0.76
SCHEMBL28610547 0.74 TDP1 (0.41) HIF1ATSHRHPGDTDP1
SCHEMBL13789598 0.72 HIF1A (0.41) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL3911215 0.72 HIF1A (0.41) HIF1ATSHRFAAHTRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110678534-B Lubricant composition containing hexene-based oligomers 切弗朗菲利浦化学公司 2022-02-11 CN disclosed
CN-107922540-B Ziegler-NATTA (ZIEGLER-NATTA) -metallocene dual catalyst system with activator-support 切弗朗菲利浦化学公司 2021-05-14 CN disclosed
CN-112672821-A Method for producing fluorinated solid oxides and use thereof in metallocene-based catalyst systems 切弗朗菲利浦化学公司 2021-04-16 CN disclosed
CN-108026220-B Heterogeneous ziegler-natta catalyst with fluorinated silica-coated alumina 切弗朗菲利浦化学公司 2020-10-27 CN disclosed
CN-110678534-A Lubricant composition containing hexene-based oligomers 切弗朗菲利浦化学公司 2020-01-10 CN disclosed