SCHEMBL28362167

SCHEMBL28362167

CC1(C)CC=C(CCNC(=O)c2ccccn2)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
ALDH1A1 P00352 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 4/20 0.47
EPHX2 P34913 1/20 0.47
ALOX15 P16050 2/20 0.46
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29650391 1.00 KMT2A (0.50) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL28944559 0.87 KMT2A (0.39) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL29650399 0.87 KMT2A (0.49) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL28362023 0.87 KMT2A (0.49) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL28361992 0.80 RAB9A (0.64) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL29650420 0.80 RAB9A (0.64) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL28361969 0.79 RAB9A (0.70) SMN1; SMN2ALDH1A1NPC1RAB9AALOX15
SCHEMBL29650441 0.79 RAB9A (0.70) SMN1; SMN2ALDH1A1NPC1RAB9AALOX15
SCHEMBL29650452 0.78 RAB9A (0.68) SMN1; SMN2ALDH1A1NPC1RAB9AALOX15
SCHEMBL29650456 0.78 RAB9A (0.68) SMN1; SMN2ALDH1A1NPC1RAB9AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818630-A Synthesis method of conjugated (E) -3-cycloalkenyl acrylate derivative 西南大学 2020-02-21 CN claimed
CN-110818630-B Synthesis method of conjugated (E) -3-cycloalkenyl acrylate derivative 西南大学 2022-06-10 CN disclosed
CN-110818630-A Synthesis method of conjugated (E) -3-cycloalkenyl acrylate derivative 西南大学 2020-02-21 CN disclosed