Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836235 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL5566856 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Styramate SCHEMBL487238 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Styramate SCHEMBL22716369 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL4954685 | 0.84 | CHRM1 (0.53) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL28397665 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Styramate SCHEMBL13879238 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL10362252 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL11244967 | 0.83 | CA12 (0.57) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL11337335 | 0.82 | ALDH1A1 (0.70) | SMN1; SMN2LMNABCAT2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082729-A | PROCESS FOR THE PREPARATION OF OXYMETHYLENE POLYMERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | claimed |
| EP-2248799-B1 | PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYL)-2-HYDROXY-ETHYL CARBAMATES | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-05-20 | — | — | EP | disclosed |
| EP-2248799-A1 | Process for preparing 2-(substituted phenyl)-2-hydroxy-ethyl carbamates | Ortho-McNeil Pharmaceutical, Inc. (US) | 2010-11-10 | — | — | EP | disclosed |
| EP-1461309-A1 | PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYL) - 2 - HYDROXY-ETHYL CARBAMATES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003053916-A1 | PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYL) - 2 - HYDROXY-ETHYL CARBAMATES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| US-4082729-A | PROCESS FOR THE PREPARATION OF OXYMETHYLENE POLYMERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |