Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.39 |
| ▸ | CDC25B | P30305 | 8/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132819 | 1.00 | HTR1A (0.41) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12605355 | 0.89 | TACR2 (0.43) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12605362 | 0.89 | PTPN1 (0.43) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12605363 | 0.88 | HTR1A (0.40) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12605361 | 0.88 | HTR1A (0.41) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2131277 | 0.87 | HTR1A (0.39) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2131583 | 0.87 | PTPN1 (0.43) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12605357 | 0.86 | SSTR1 (0.42) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL1776327 | 0.83 | SLC5A2 (0.39) | HTR1ASSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2131482 | 0.83 | PTPN1 (0.41) | HTR1ASSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147430-A2 | NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2010-12-23 | — | — | WO | disclosed |