Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19347953 | 1.00 | LAP3 (0.37) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| SCHEMBL16681924 | 0.83 | LAP3 (0.33) | LAP3ANPEPERAP1GRIN2DGRIN3B | |
| SCHEMBL16685333 | 0.83 | LAP3 (0.33) | LAP3ANPEPERAP1GRIN2DGRIN3B | |
| SCHEMBL299589 | 0.83 | LAP3 (0.39) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| SCHEMBL299588 | 0.83 | LAP3 (0.39) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| SCHEMBL28444493 | 0.83 | CA4 (0.46) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| SCHEMBL2382256 | 0.83 | CA4 (0.46) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| SCHEMBL3722209 | 0.82 | LAP3 (0.44) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| SCHEMBL3725774 | 0.82 | LAP3 (0.44) | LAP3CYP2D6CYP2C9CYP2C19ANPEP | |
| Ammonia Solution, Strong SCHEMBL7772821 | 0.81 | CA4 (0.44) | LAP3CYP2D6CYP2C9CYP2C19ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804072-B | Dioxolane analogues of uridine for use in the treatment of cancer | 美迪维尔公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-110790789-B | Dioxolane analogues of uridine for use in the treatment of cancer | 美迪维尔公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-111269264-A | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-107074826-B | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-110804072-A | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-02-18 | — | — | CN | disclosed |
| CN-110790789-A | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-02-14 | — | — | CN | disclosed |