SCHEMBL28366152

SCHEMBL28366152

CCc1cccc([N+](=O)[O-])c1.OP(O)(O)=S

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
LMNA P02545 2/20 0.50
GAA P10253 1/20 0.49
ALDH1A1 P00352 5/20 0.47
ACHE P22303 1/20 0.47
ALOX15 P16050 1/20 0.47
MAOB P27338 2/20 0.47
MAOA P21397 1/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
F2 P00734 1/20 0.47
PYCR1 P32322 1/20 0.47
PTPRC P08575 1/20 0.47
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132216 0.90 TSHR (0.67) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL29385659 0.90 TSHR (0.67) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL28623713 0.89 TSHR (0.48) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL4171963 0.86 TSHR (0.62) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL3512311 0.84 TSHR (0.49) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL12826413 0.80 TSHR (0.54) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
Dinitrophenylene SCHEMBL28012196 0.80 TSHR (0.63) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL10557823 0.79 TSHR (0.54) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
Dinitrophenylene SCHEMBL27502168 0.79 CYP2D6 (0.61) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL10555759 0.77 TSHR (0.51) TSHRCYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531622-B Anthranilate compound or salt thereof, agricultural and horticultural bactericide containing anthranilate compound, and method for using same 日本农药株式会社 2020-03-20 CN disclosed