SCHEMBL28623713

SCHEMBL28623713

CCOP(O)(O)=S.CCc1cccc([N+](=O)[O-])c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
CYP2C19 P33261 3/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP1A2 P05177 2/20 0.46
MAPT P10636 4/20 0.45
ALDH1A1 P00352 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP3A4 P08684 2/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RECQL P46063 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAOB P27338 2/20 0.44
MAOA P21397 1/20 0.44
F2 P00734 1/20 0.44
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28366152 0.89 TSHR (0.56) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL3512311 0.88 TSHR (0.49) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL132216 0.82 TSHR (0.67) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL29385659 0.82 TSHR (0.67) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL4923182 0.81 GRM8 (0.51) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
Hydrochloric Acid SCHEMBL4171963 0.79 TSHR (0.62) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL479034 0.76 CCNT1 (0.59) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
Dinitrophenylene SCHEMBL27502168 0.75 CYP2D6 (0.61) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL2852943 0.74 NPSR1 (0.46) TSHRCYP2C19CYP2D6CYP2C9CYP1A2
SCHEMBL27233619 0.74 CCNT1 (0.54) TSHRCYP2C19CYP2D6CYP2C9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108348886-B Method for preparing microcapsules by double emulsification 卡莉西亚公司 2021-09-10 CN disclosed