Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380958 | 1.00 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL30987621 | 1.00 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL2380961 | 1.00 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL14915162 | 0.89 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL21845196 | 0.89 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL14915166 | 0.89 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL14915165 | 0.89 | PTPN1 (0.49) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL31239774 | 0.87 | PTPN1 (0.48) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL31000507 | 0.86 | PTPN1 (0.47) | PTPN1NR1H2NR1H3MMP2ANPEP | |
| SCHEMBL29851000 | 0.86 | PTPN1 (0.47) | PTPN1NR1H2NR1H3MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |
| WO-2010062821-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-06-03 | — | — | WO | disclosed |