SCHEMBL28366198

SCHEMBL28366198

O=C(O)c1ccc(-c2ccc(C(=O)O)c(OF)c2OF)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C8 P10632 3/20 0.48
FOLH1 Q04609 1/20 0.45
BCL2L1 Q07817 1/20 0.43
BAD Q92934 1/20 0.43
PTPN11 Q06124 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
SRD5A2 P31213 1/20 0.40
HSD17B10 Q99714 2/20 0.39
TTR P02766 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28884090 0.81 FOLH1 (0.51) FOLH1PTPN11HDAC6
SCHEMBL30719082 0.80 CYP2C8 (0.52) CYP2C8FOLH1PTPN11SRD5A2HSD17B10
SCHEMBL29152929 0.80 CYP2C8 (0.52) CYP2C8FOLH1PTPN11SRD5A2HSD17B10
SCHEMBL21708057 0.74 CYP2C8 (0.50) CYP2C8FOLH1PTPN11SRD5A2HSD17B10
SCHEMBL30585141 0.74 BCL2L1 (0.52) CYP2C8FOLH1BCL2L1BADPTPN11
SCHEMBL26639280 0.74 BCL2L1 (0.52) CYP2C8FOLH1BCL2L1BADPTPN11
SCHEMBL141962 0.72 FOLH1 (0.50) CYP2C8FOLH1BCL2L1BADPTPN11
SCHEMBL20475496 0.72 HNF4A (0.52) CYP2C8FOLH1BCL2L1BADTP53
SCHEMBL29787168 0.72 HNF4A (0.52) CYP2C8FOLH1BCL2L1BADTP53
SCHEMBL7633480 0.71 FOLH1 (0.67) CYP2C8FOLH1BCL2L1BADPTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869848-A Laminated structure, dry film, and flexible printed circuit board 太阳油墨制造株式会社 2020-03-06 CN disclosed