Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370719 | 1.00 | ATM (0.41) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL4707610 | 0.78 | ATM (0.41) | ATM | |
| SCHEMBL4709077 | 0.78 | ATM (0.41) | ATM | |
| SCHEMBL4707613 | 0.78 | ATM (0.41) | ATM | |
| SCHEMBL28366056 | 0.77 | ATM (0.36) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28370233 | 0.77 | ATM (0.36) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28557982 | 0.76 | L3MBTL3 (0.45) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL425737 | 0.76 | — | — | |
| SCHEMBL28723055 | 0.75 | ATM (0.38) | ATMDPP4DPP8DPP9DPP7 | |
| SCHEMBL28649982 | 0.74 | DPP4 (0.44) | ATMDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110753692-A | Chemical compounds as H-PGDS inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-02-04 | — | — | CN | disclosed |