Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17029101 | 0.79 | SMN1; SMN2 (0.45) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL324644 | 0.79 | SLC6A3 (0.39) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28056335 | 0.77 | BTK (0.31) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4842646 | 0.74 | CYP1A2 (0.71) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL3636025 | 0.74 | — | — | |
| SCHEMBL6864414 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1715276 | 0.72 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL4974945 | 0.71 | — | — | |
| SCHEMBL18641383 | 0.70 | KDM4E (0.56) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL1877939 | 0.70 | KMT2A (0.50) | CYP1A2CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107043375-B | Novel method for preparing dasatinib and intermediate thereof | 江苏食品药品职业技术学院 | 2020-03-20 | — | — | CN | disclosed |